The aim and objective of this study was to assess the compliances towards adherence to radiation safety measures among medical professionals who working under radiation zone. A cross-sectional study was performed at tertiary healthcare centre Gurgaon. The targeted peoples included in this study; physicians, nurses, technician and other OT staff working in the operating area under C-Arm. Result: The total number of participants included in this study was 120 including physician (30), technician (25), nurse (15), and trainee students (50). Toward adherence to safety norms and guidelines, 98% were used personnel protective equipment such as lead apron, 97% wear the TLD Badge during radiation exposure, and 85% were maintain the distance between source to personnel’s about 1-1.5 meter during radiation exposure. Discussion: The adherence to safety precaution in the radiology department is an essential factor to ensure the good practice in radiology department. It is also a key factor to assess the continual quality improvement in the radiology department. For various accreditation and approval such NABH, JCI etc. adherence to safety precaution plays an important role.