FES is a multi-systemic disorder, and its pathogenesis remains unclear to date, though well accepted-mechanical and biochemical mechanism maybe explained. Imaging plays a major role in confirming the diagnosis. Because of its uncommon presentation-here we are reporting a case of a young male with multiple long bone fractures. He was admitted to our Intensive Care Unit, was diagnosed with cerebral fat embolism syndrome (FES) based on clinical suspicion and imaging features. CT brain was normal. Due to strong clinical suspicion MRI was done. Fat embolism was confirmed by typical imaging features on magnetic resonance imaging (MRI) The patient was ventilated and managed appropriately. Surgery was done for the fractures and discharged.