Intussusception is a rare condition in adults and accounts for 1-5% of intestinal obstruction cases. Its clinical symptoms are poor and misleading. Medical imaging is one of the primary means that facilitates their diagnosis. The purpose of this article is to describe two rare cases of intestinal intussusception in adults. We report two cases of acute and chronic intestinal intussusception in adults, revealed by an occlusive syndrome and diagnosed by Computed Tomography. Their causes are organic, malignant and rare. The first case is a metastasis of a pulmonary adenocarcinoma and the second is an Epstein Barr Virus (EPV) positive Burkitt lymphoma.